Rose has been mentioned in Iranian traditional medicine as an anti-depressant, anti-anxiety with gentle aroma but powerful anti-depressant, enhancer of libido in women and men, skincare as well as a stimulant effect on the human brain. Rose essential oil has been used to improve mood for a long time which results in today's studies refer to these properties. So it is a natural antidepressant supplement. Rose essential oil aroma, as an antidepressant supplement can help reduce anxiety and reduce the level of stress hormone to an acceptable level. In a study, the use of Rose essential oil for 8 weeks, reduced the symptoms of depression in depressed men. In another study on women who gave birth for the first time, showed that the aroma of Rose essential oil reduces anxiety. In addition, Rose Essential Oil is an effective ingredient in increasing the libido of men and women. In studies on methadone addicted men, depressed men and women, and those who use antidepressants, the use of Rose essential oil has improved sexual dysfunctions and increased levels of male sex hormone (testosterone) in men.
In Iranian medicine, from a long time ago, Valerian has been used as a natural sedative, Natural Tranquilizer, hypnotic, anti-depressant, and anticonvulsant. Among St John's-wort properties, sedative effects are relevant to volatile oils include Valerianum and Valerian Acid and Valproate compounds. In addition, Valerian acid inhibits the enzyme responsible for catabolism and GABA decomposition, which increases the concentration of GABA in the brain so reduces the activity of various brain nuclei and causes calming effects. Valerian tablet as a Natural Tranquilizer is shown to be more effective than Diazepam drug in a clinical study. So you can use it as a herbal & Natural anti anxiety supplement. Also, laboratory and clinical experiences have proven the anxiolytic and sedative effects of Passionate Extract, which makes it more effective as Natural anti anxiety.
This product consists of 3 prominent herbs, Valerian, St. John's Wort and Passion. Human clinical trials show that the plant Valerian has sedative effects, which are mostly related to its volatile oils. Biochemical studies show that Valerenic Acid in this herb inhibits Gamma-Aminobutyric Acid (GABA) catabolism in the synaptic connections in the central nervous system. This leads to high concentrations of GABA in the brain tissue which causes sedative effects. The antidepressant effects of St. John's Wort are due to its Hyperforin compounds, which inhibit the absorption of norepinephrine, dopamine, glutamate, and GABA. Also, Bioflavonoids and Amentoflavone that are found in this plant, inhibit serotonin receptors, particularly 5- HT (1D) and 5—HT(2C). In addition, it reduces Corticotropin-releasing hormone (CRH) and the release of Interleukin 6. Furthermore, the anxiolytic and sedative effects of Passion are due to Flavonoids including Apigenin and Chrysin, which bind to GABA receptors A and inhibit the reuptake of GABA neurotransmitters. Finally, GABA concentration increases leading to soothing and anxiolytic effects.
Saffron is the most expensive herbal medicine in the world and is recognized as appetizing, sedative and hypnotic in traditional medicine. Also, saffron stimulates gastric juice secretion and helps digestion. Saffron can control depression and relieve pain due to the presence of Safranal and Crocin. These two active ingredients have the same effect as Fluoxetine, and prevent dopamine, norepinephrine and serotonin reabsorption and thus exerts its antidepressant effect. Recent researches have been shown that Saffron is effective in preventing and improving cancer, which is due to the presence of Lycopene and Carotene in this plant. Its mechanism of action is due to several anti-oxidant activities, such as limiting the synthesis of RNA and DNA in cancer cells and interrupting the chain reaction of free radicals. Also, Crocin and Crocidine, are potent antioxidants that prevent membrane degradation and the genetic content of sperm by free oxygen radicals "ROS" and thereby increase the mobility and improve the morphology of sperm and improve male sexual function. Also, due to the fact that one of the most important reasons for sexual problems is psychological and depressive factors, this Product with sedation and anti-depressive effects can greatly enhance the return and increase of libido.