Crataegus Oral Drop (Blood Pressure Reducer)

Red Hawthorn with a set of flavonoids and procyanidins has antioxidant and inotropic positive effects and its primary activity is to increase coronary blood flow and dilate both peripheral and coronary blood vessels leading to its use in angina. Hawthorn’s positive inotropic action may also be due to inhibition of Myocardial Na+/K+ ATPase and its ability to inhibit the enzyme Phosphodiesterase (PDE) which ultimately results in an increase in intracellular cyclic nucleotides and a subsequent positive inotropic effect. Hawthorn also has Angiotensin-converting enzyme (ACE) which has the ability to regulate blood pressure. In the largest trial to date, 80 patients with type 2 Diabetes, mean age 60 years, who had DBP(diastolic blood pressure) levels of 85-95 mm Hg, were treated with either Hawthorn extract or placebo for 16 weeks. The patients who were taken Hawthorn had a significant reduction in mean DBP after 16 weeks in contrast with those who were taken placebo(-2.6 vs +0.5 mm Hg, P = .035).

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Description

Red Hawthorn with a set of flavonoids and procyanidins has antioxidant and inotropic positive effects and its primary activity is to increase coronary blood flow and dilate both peripheral and coronary blood vessels leading to its use in angina.
Hawthorn’s positive inotropic action may also be due to inhibition of Myocardial Na+/K+ ATPase and its ability to inhibit the enzyme Phosphodiesterase (PDE) which ultimately results in an increase in intracellular cyclic nucleotides and a subsequent positive inotropic effect. Hawthorn also has Angiotensin-converting enzyme (ACE) which has the ability to regulate blood pressure.
In the largest trial to date, 80 patients with type 2 Diabetes, mean age 60 years, who had DBP(diastolic blood pressure) levels of 85-95 mm Hg, were treated with either Hawthorn extract or placebo for 16 weeks. The patients who were taken Hawthorn had a significant reduction in mean DBP after 16 weeks in contrast with those who were taken placebo(-2.6 vs +0.5 mm Hg, P = .035).

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* Anti congestive heart failure (CHF)
* Anti angina pectoris
* Hypertention reliver

Oral Drop 30 ml

Hawthorn (Crataegus oxyacantha L.) extract

Flavonoids

Initial dose (first 3-4 days): Take 60-70 drops each time, 3 times a day.
Maintenance dose: Take 25 drops each time, 3 times a day.
It is better to dilute this oral drop with a little water and then take it.

The primary activity of hawthorn is to increase coronary blood flow and dilate both peripheral and coronary blood vessels leading to its use in angina.
Hawthorn’s positive inotropic action may also be due to inhibition of myocardial Na+/K+ ATPase and its ability to inhibit the enzyme phosphodiesterase (PDE) which ultimately results in an increase in intracellular
cyclic nucleotides and a subsequent positive inotropic effect.
Hawthorn has also to have angiotensin converting enzyme (ACE) inhibiting effect and has the ability to regulate blood pressure.

In the first 3 months of pregnancy, children less than 12 years old, GI illnesses and sensitivity to this drug.

* Side effects are seldom reported, if the normal and recommended dose is used.
* Higher doses can cause hypotension, bradycardia, sedation, nausea, sweating, dizziness and skin rash (usually on the palm).
* Since This drop inhibits the action of ACE and ultimately prevents synthesis of aldosterone hormone, long term use of this drug can lead to hyperkalemia.

* This drop may have synergism effect on cardiac glycosides such as Digoxin.
* Concurrent use of This drop with ß blockers (such as Propranolol) may cause hypertension.
* This drop may increase the risk of bleeding if taken with antiplatelet agents.
* Cardiovascular effect of this drug is increased if vitamin B6, onion, garlic and magnesium supplements are used concurrently.
* This drop has interaction with Cisapride and should not be used concurrently with this medicine.

* Store at room temperature (15-30ºC).
* Protect from direct light and heat.
* Keep out of the reach of children.

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