Gastrolit Soft Capsule (Anti Bowel Disorders)
Iranian (Shirazi) Thyme is a species endemic of Iran, which has been used in traditional medicines for a long time due to its disinfectant, analgesic and carminative properties .and is common for treatment of Irritable Bowel Syndrome(IBS). In a clinical trial, the effect of Gastrolit drop was evaluated in 53 IBS patients, which after 2 weeks, the treatment of all symptoms of the disease was significantly effective.
Natural IBS Remedies
Iranian (Shirazi) Thyme is a species endemic of Iran, which has been used in traditional medicines for a long time due to its disinfectant, analgesic and carminative properties .and is common for treatment of Irritable Bowel Syndrome(IBS).
In a clinical trial, the effect of Gastrolit drop was evaluated in 53 IBS patients, which after 2 weeks, the treatment of all symptoms of the disease was significantly effective.
Adjuvant treatment for Irritable Bowel Syndrome (IBS) symptoms including pain, flatulence, heartburn, GERD and changes in stool consistency.
30 Soft Capsules – 20 mg
Iranian Thyme (Zataria multiflora) essential oil
Thymol and carvacrol
Take 1 capsule every 8 hours.
Irritable Bowel Syndrome (IBS) is one of the most prevalent disorders of the digestive system, which is characterized by pain and/or disturbances in the bowels along with irregularities in defecation manifested by alternating episodes of diarrhea and constipation. Among the methods of diagnosis for this disorder is the diagnostic criteria Rome III. It includes: recurrent pain or disturbance in the bowels for at least 3 days in the previous 3 months, along with at least two of the following criteria: Improvement with defecation; Onset associated with a change in frequency of stool; Onset associated with a change in form (appearance) of stool.
Based on Rome III diagnostic criteria, currently about 5-10% of the population in developed countries suffer from IBS, mostly seen in women and the third and fourth decades of life. Unfortunately, treatment options are limited for patient suffering from IBS, which is partly due to the fact that the mechanism and causes of this disorder are still not fully known.
Use of herbal medications is common for treatment of IBS symptoms. Based on the results of a controlled double-blind prospective study with placebo control, after 4 weeks of treatment with capsules containing mint essential oil, 75% of patients manifested a 50% reduction in symptoms (in comparison to 38% in the placebo group). In comparison to the beginning of the study, unlike the group taking the placebo, there was statistically significant reduction in symptoms in the group taking the mint essential oil capsule 4 weeks after the commencement of the treatment and 4 weeks after its end.
Iranian (Shirazi) thyme is a species endemic to Iran, which has long been used in folk medicine due to its disinfectant, analgesic and carminative properties.
The analgesic properties of the hydro-alcoholic extract and the essential oil of Iranian thyme has been studied in rat and mice using writhing, tail flick and formalin test. The hydro alcoholic extract (500 mg/kg, i.p.) and the essential oil (0.3 ml/kg, i.p) of Iranian thyme have demonstrated its analgesic properties in the tail flick test (p<0.05). They have also manifested their analgesic effects in writhing and formalin tests. The overall properties of this plant as demonstrated through the mentioned tests are testimonies to the central and peripheral analgesic effects of Iranian thyme. In another study using laboratory animals, the essential oil of thyme leaves demonstrated dose-dependent inhibition of contractions caused by Kel in isolated ileum of rats, which resembles the effects of dicyclomine. In a multicenter randomized clinical trial, the effect of Gastrolit oral drop was evaluated in 53 patients, for whom a definitive diagnosis of IBS had been made using Manning criteria. Based on the results of this study, after 2 weeks of treatment with 20 drops, three times a day, Gastrolit drop was effective in treatment of all symptoms of IBS (p<0.002) and in most cases both the patients and physicians were satisfied with the medication. In a randomized, placebo-controlled double-blind clinical trial to evaluate the efficacy of Gastrolit soft capsule in treatment of IBS symptoms, patients admitted to the gastroenterology clinic of Tehran's Imam Khomeini hospital were examined by a gastroenterologist; in case of need, endoscopy and sonography inspections were performed, and those patients whose IBS diagnosis was made according to Manning criteria were entered into the study. Patients with active peptic ulcer, organic disorders, cancer and systemic disorders were excluded. In this study, 58 patients who were entered into the study, were administered either Gastrolit soft capsule or placebo soft capsule, which were to be taken every 8 hours. After 2 and 4 weeks after the commencement of the treatment, the patients' clinical symptoms were evaluated and the results were statistically analyzed using t-tests coupled with a Wilcoxon matched pairs signed-rank test. Based on the results of this study, two weeks after the treatment, the percentage of improvement in symptoms was more favorable in the medication group compared to the placebo group. The researchers came to the conclusion that Gastrolit soft capsule is effective in elimination of IBS symptoms.
* Thyroid disorders: theoretically, thyme can decrease thyroid hormone levels. Patients receiving thyroid replacement therapy or those who take anti-thyroid medications should take products containing thyme with caution and need to be monitored.
* In patients with cardiac and respiratory disorders, take with caution and consult your physician.
With the suggested dosage and administration guideline, no adverse effects have been reported. Nonetheless, in case of overdose, or in sensitive individuals, the thymol present in the product may cause vertigo, headache, nausea, vomiting, muscle weakness, decrease in cardiac function, respiratory system and body’s temperature. In case these adverse effects occur, discontinue use and consult your physician.
* In prolonged use, discontinue use for 1-2 days per every week of usage, resume as before.
* Store at room temperature (15-30ºC).
* Protect from direct light and heat.
* Keep out of the reach of children.