Lomex Soft Capsule (Anti Diarrhea)

In traditional medicine, Summer Savory is mentioned as an anti-Diarrhea and antispasmodic herb. The terpenes and terpenoids present in essential oil of Summer Savory have antispasmodic and antimicrobial properties, therefore it can also be used in the case of microbial Diarrheas. In a clinical trial, 56 patients with type I Diarrhea, took Lumex soft capsule or placebo for 3 days, one soft capsule every 8 hours. The degree of recovery in the first 24 hours in the Lumex soft capsule group was 63% and in the placebo group 25.9%. Also the prevalence of cramps 24 hours after the beginning of treatment was 35.7% in the Lumex soft capsule group and 68% in the placebo group.

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Description

Description

Diarrhea pill

Diarrhea is a condition in which the patient has at least three times a day excretion in liquid form. It can take a few days and cause dehydration of the body, which occurs after the loss of liquids. The symptoms of dehydration usually start by the loss of the natural tension of the skin. This situation can advance and may lead to a reduction in urine, pallor, rapid heart rate. But excretion in liquid form, without water, can be normal in children who feed on mother’s milk. diarrhea pill natural treatment is a good approach to get rid of this disease.

The main cause of diarrhea is the infection of the intestine. intestine infection may cause by these factors: viruses, bacteria, parasites or situations known as diarrhea and vomiting. These infections usually come from contaminated food with feces or transmitted from an infected person. We Can David this disease into three models. Short-term watery diarrhea, short-term bloody diarrhea, and if continued for over two weeks, it is known as stable diarrhea. The short-term watery diarrhea could associate with cholera. Short – term bloody diarrhea is a situation known as Dysentery. A number of non-infection factors may also lead to diarrhea. These factors include Thyroid, lactose intolerance, inflammatory bowel disease, consumption of some medications, irritable bowel syndrome, and etc.

 

Savory and Diarrhea

The Savory contains about 1% of the essential oils made up of materials such as Carvacrol, thymol, and Company.

Other ingredients of Savory contain different vitamins and minerals, depending on the condition that the Savory has been cultivated.

Savory due to its ingredients, has anti-fungi, anti-inflammatory, and anti-diarrhea properties. High amounts of fiber in the Savory is helpful with improving bowel movements to prevent and treatment of diarrhea.

Savory has a warm nature and boosts stomach and facilitates excretion and also has anti-flatulence properties. In addition, Savory is very good for the treatment of diarrhea and it is a very strong disinfectant.

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Indications

Adjuvant treatment for non-infectious diarrhea (reduction in cramps, number of trips to the toilet and duration of the diarrhea)

Dosage form and packaging

30 Soft Capsules – 50 mg

Composition

Summer Savory (Satureja hortensis) essential oil

Effective Ingredients

Thymol and carvacrol

Suggested Use

Take 1 capsule every 8 hours.

Pharmacology

Irritable Bowel Syndrome (IBS) is one of the most prevalent disorders of the digestive system, which is characterized by pain and/or disturbances in the bowels along with irregularities in defecation manifested by alternating episodes of diarrhea and constipation. Among the methods of diagnosis for this disorder is the diagnostic criteria Rome III. It includes: recurrent pain or disturbance in the bowels for at least 3 days in the previous 3 months, along with at least two of the following criteria: Improvement with defecation; Onset associated with a change in frequency of stool; Onset associated with a change in form (appearance) of stool.
Based on Rome III diagnostic criteria, currently about 5-10% of the population in developed countries suffer from IBS, mostly seen in women and the third and fourth decades of life. Unfortunately, treatment options are limited for patient suffering from IBS, which is partly due to the fact that the mechanism and causes of this disorder are still not fully known.
Use of herbal medications is common for treatment of IBS symptoms. Based on the results of a controlled double-blind prospective study with placebo control, after 4 weeks of treatment with capsules containing mint essential oil, 75% of patients manifested a 50% reduction in symptoms (in comparison to 38% in the placebo group). In comparison to the beginning of the study, unlike the group taking the placebo, there was statistically significant reduction in symptoms in the group taking the mint essential oil capsule 4 weeks after the commencement of the treatment and 4 weeks after its end.
Iranian (Shirazi) thyme is a species endemic to Iran, which has long been used in folk medicine due to its disinfectant, analgesic and carminative properties.
The analgesic properties of the hydro-alcoholic extract and the essential oil of Iranian thyme has been studied in rat and mice using writhing, tail flick and formalin test. The hydro alcoholic extract (500 mg/kg, i.p.) and the essential oil (0.3 ml/kg, i.p) of Iranian thyme have demonstrated its analgesic properties in the tail flick test (p<0.05). They have also manifested their analgesic effects in writhing and formalin tests. The overall properties of this plant as demonstrated through the mentioned tests are testimonies to the central and peripheral analgesic effects of Iranian thyme. In another study using laboratory animals, the essential oil of thyme leaves demonstrated dose-dependent inhibition of contractions caused by Kel in isolated ileum of rats, which resembles the effects of dicyclomine. In a multicenter randomized clinical trial, the effect of Gastrolit oral drop was evaluated in 53 patients, for whom a definitive diagnosis of IBS had been made using Manning criteria. Based on the results of this study, after 2 weeks of treatment with 20 drops, three times a day, Gastrolit drop was effective in treatment of all symptoms of IBS (p<0.002) and in most cases both the patients and physicians were satisfied with the medication. In a randomized, placebo-controlled double-blind clinical trial to evaluate the efficacy of Gastrolit soft capsule in treatment of IBS symptoms, patients admitted to the gastroenterology clinic of Tehran's Imam Khomeini hospital were examined by a gastroenterologist; in case of need, endoscopy and sonography inspections were performed, and those patients whose IBS diagnosis was made according to Manning criteria were entered into the study. Patients with active peptic ulcer, organic disorders, cancer and systemic disorders were excluded. In this study, 58 patients who were entered into the study, were administered either Gastrolit soft capsule or placebo soft capsule, which were to be taken every 8 hours. After 2 and 4 weeks after the commencement of the treatment, the patients' clinical symptoms were evaluated and the results were statistically analyzed using t-tests coupled with a Wilcoxon matched pairs signed-rank test. Based on the results of this study, two weeks after the treatment, the percentage of improvement in symptoms was more favorable in the medication group compared to the placebo group. The researchers came to the conclusion that Gastrolit soft capsule is effective in elimination of IBS symptoms.

Contraindications

* pregnancy
* Lactation
* Thyroid disorders: theoretically, thyme can decrease thyroid hormone levels. Patients receiving thyroid replacement therapy or those who take anti-thyroid medications should take products containing thyme with caution and need to be monitored.
* In patients with cardiac and respiratory disorders, take with caution and consult your physician.

Adverse Effects

With the suggested dosage and administration guideline, no adverse effects have been reported. Nonetheless, in case of overdose, or in sensitive individuals, the thymol present in the product may cause vertigo, headache, nausea, vomiting, muscle weakness, decrease in cardiac function, respiratory system and body’s temperature. In case these adverse effects occur, discontinue use and consult your physician.

Interactions

Not reported

Recommendations

* In prolonged use, discontinue use for 1-2 days per every week of usage, resume as before.
* Store at room temperature (15-30ºC).
* Protect from direct light and heat.
* Keep out of the reach of children.